Description
General information on Tamoxfeine Ebewe 20 mg in Italy
Interaction: increases the effect of indirect anticoagulants (requires careful monitoring to adjust the dose of anticoagulants). cytotoxic agents increase the risk of thrombosis. The combined use of tamoxifen and tegafur can cause chronic active hepatitis and cirrhosis. The concomitant use of tamoxifen with others. hormonal drugs (contraceptives, especially estrogensoderjath) leads to a weakening of the specific effects of both drugs. Drugs that reduce calcium excretion (such as the number of thiazide diuretics) can increase the risk of hypercalcemia. Antacids, H2 blockers of histamine receptors and Dr. LS which reduce gastric acidity, can cause premature dissolution and loss of the protective effect of enteric tablets. The interval between tamoxifen and these drugs should be 1-2 hours.
Features Tamoxfeine Ebewe 20 mg in Italy
Side effects: oxalgia, pain in injuries, fever; loss of appetite, nausea, vomiting, constipation or diarrhea, and in rare cases – fatty liver, cholestasis, hepatitis; redness of the skin with a feeling of heat; leukopenia, thrombocytopenia, thrombosis, thromboembolism, thrombophlebitis; skin rash, dry skin, the increase in the size of soft tissue structures, sometimes accompanied by severe lesions erythema and surrounding areas (usually disappear within 2 weeks); hypercalcemia, peripheral edema (associated with fluid retention), alopecia, weight gain; depression, headache, dizziness, myasthenia gravis, fatigue, drowsiness, confusion; loss of visual acuity, corneal opacities, cataracts, retinopathy, optic neuritis. Women – endometrial hyperplasia, a reversible development of cystic tumors, vaginal discharge, metrorrhagia, dysmenorrhea, genital itching, amenorrhea.
Interaction with other drugs in Italy
Warning: Before treatment, women should undergo a thorough gynecological (with the exception of pregnancy) and physical examination. Tamoxifen induces ovulation, which increases the risk of pregnancy, so women of childbearing age must use reliable (hormonal) methods of contraception during treatment and for 3 months after treatment. During therapy should be periodically monitored indicators of blood clotting, blood calcium concentration, blood picture (white blood cells, platelets), liver function, blood pressure, inspect an ophthalmologist – every 3 months, gynecological examination (with the appearance of bloody vaginal discharge or vaginal bleeding the drug should be stopped). In patients with bone metastases periodically during the initial treatment period should be determined in serum calcium concentration (in the case of severe hypercalcemia tamoxifen should be discontinued). It is ineffective in treating patients with metastatic disease (especially in the liver). Buy Tamoxfeine Ebewe 20 mg If signs of thrombosis in the lower limbs (leg pain or swelling), thromboembolism, branches of the pulmonary artery (dyspnea), the drug should be discontinued. Patients with hyperlipidemia in the treatment need to control the concentration of cholesterol and triglycerides in serum. During the treatment period must be careful when driving and other lesson. Potentially dangerous activities that require high concentration and psychomotor speed reactions.
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